Ultimately, a platform like WordPress - particularly using something like HeadSpace gives you a lot of control over how search engines interact with your site.
The more you can CONTRIBUTE to other high-ranking blogs that allow DOFOLLOW, the more you can increase the value of your own site. Using a mix of DOFOLLOW and NOFOLLOW on your own outbound linking *from* your site tells search engines that you are working to moderate your content a bit which seems to also have a value.