I'm not sure that you would want a "One Size Fits All Solution" in this situation..
If I understand your request correctly you want a software or system that you plug your content in and it creates a website for you.

While in theory it sounds like a great option this would end up being nothing more then a template site. There really is no way that you could create a system like this that could encompass the number of niche possibilities.
Now that doesn't mean you don't have options available but it's going to include hiring an experienced consultant to help with the site design, the system design, and your overall strategy design...