I believe it is a waste of time to submit to more than just the big ones, like EzineArticles, GoArticles and Articledashboard to name a few.
It is much better to focus on writing an article that SE's will like (keyword based), and prevent the duplicate content situation where your articles could be dismissed altogether.
One way some people are using is send your articles to big ones like Ezine Articles, GoArticles, Amazines, and so on, with link to your money site in bio section. Then send the second batch of article to other article directories with link to your articles you sent to big articles directories in first batch.